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Title

Sarcoptes scabiei: Specific immune response to sarcoptic mange in the Iberian ibex Capra pyrenaica depends on previous exposure and sex

AuthorsSarasa, Mathieu; Rambozzi, Luisa; Rossi, Luca; Meneguz, P.G.; Serrano, Emmanuel; Granados, José E.; González, Francisco José; Fandos, Paulino; Soriguer, Ramón C. ; González, Georges; Joachim, Jean; Pérez, Jesús M.
Issue Date2010
PublisherAcademic Press
CitationExperimental Parasitology 124: 265- 271 (2010)
AbstractHost acquired immunity is a critical factor that conditions the survival of parasites. Nevertheless, there is a shortage of data concerning inter-individual immunological inequalities in wild mammals. Sarcoptic mange is a widespread parasitosis that severely affects mammals such as the Iberian ibex (Capra pyrenaica). Despite some work on the subject, the immune response to sarcoptic mange infestation is still a complex and poorly understood phenomenon. To improve knowledge of the host-. Sarcoptes immunological interaction, 18 Iberian ibexes were experimentally infested. IgG levels were assessed using ELISA to test for potential factors determining the specific immune response to infestation. Previous exposure and sex appeared to affect the IgG response to infestation and our results suggest a sex-biased immunomodulation. We discuss the immunological pattern of host-. Sarcoptes interactions and also suggest further lines of work that may improve the understanding of immunological interactions of host-Sarcoptes systems. © 2009 Elsevier Inc.
URIhttp://hdl.handle.net/10261/63248
DOI10.1016/j.exppara.2009.10.008
Identifiersdoi: 10.1016/j.exppara.2009.10.008
issn: 0014-4894
Appears in Collections:(EBD) Artículos
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