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Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/60310
Title: Response functions for SIMPLEX optimization of flow-injection analysis and related techniques
Authors: Horstkotte, Burkhard; Duarte, Carlos M.; Cerdà, Víctor
Issue Date: 2010
Publisher: Elsevier
Citation: TrAC - Trends in Analytical Chemistry 29: 1224- 1235 (2010)
Abstract: Computational optimization strategies using algorithms (e.g., modified SIMPLEX method) present a fast, efficient alternative to univariant studies of chemical and physical experimental parameters of analytical flow systems.In this review, we give an overview of the applications of the SIMPLEX algorithm for optimizing analytical systems based on unsegmented flow techniques. We compare the different response functions used for evaluating the experimental data for optimization. We also discuss their advantages and shortcomings, and, with special focus on real-time applications, the problems involved in using SIMPLEX. We summarize in tabular form the analytical applications and the parameters optimized by the SIMPLEX method. © 2010 Elsevier Ltd.
URI: http://hdl.handle.net/10261/60310
Identifiers: doi: 10.1016/j.trac.2010.07.006
issn: 0165-9936
DOI: 10.1016/j.trac.2010.07.006
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