DSpace

Digital.CSIC > Biología y Biomedicina > Instituto de Bioquímica Vegetal y Fotosíntesis (IBVF) > (IBVF) Artículos >

Share

EndNote

Impact

Open Access item Arabidopsis thaliana telomeres exhibit euchromatic features

Authors:Vaquero-Sedas, M.I.
Gámez-Arjona, Francisco M.
Vega-Palas, Miguel A.
Issue Date:2011
Publisher:Oxford University Press
Citation:Nucleic Acids Research 39: 2007- 2017 (2011)
Abstract:Telomere function is influenced by chromatin structure and organization, which usually involves epigenetic modifications. We describe here the chromatin structure of Arabidopsis thaliana telomeres. Based on the study of six different epigenetic marks we show that Arabidopsis telomeres exhibit euchromatic features. In contrast, subtelomeric regions and telomeric sequences present at interstitial chromosomal loci are heterochromatic. Histone methyltransferases and the chromatin remodeling protein DDM1 control subtelomeric heterochromatin formation. Whereas histone methyltransferases are required for histone H3K9 2Me and non-CpG DNA methylation, DDM1 directs CpG methylation but not H3K92Me or non-CpG methylation. These results argue that both kinds of proteins participate in different pathways to reinforce subtelomeric heterochromatin formation. © The Author(s) 2010. Published by Oxford University Press.
URI:http://hdl.handle.net/10261/60109
Identifiers:doi: 10.1093/nar/gkq1119
issn: 0305-1048
e-issn: 1362-4962
Appears in Collections:(IBVF) Artículos

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.