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dc.contributor.authorAlmeida, Julia-
dc.contributor.authorTeodosio, Cristina-
dc.contributor.authorPedreira, C. E.-
dc.contributor.authorLópez, Antonio-
dc.contributor.authorNieto, Ana B.-
dc.contributor.authorRodríguez-Caballero, Arancha-
dc.contributor.authorJara-Acevedo, Maria-
dc.contributor.authorOrfao, Alberto-
dc.date.accessioned2012-11-08T10:50:37Z-
dc.date.available2012-11-08T10:50:37Z-
dc.date.issued2011-
dc.identifierdoi: 10.1038/leu.2010.305-
dc.identifierissn: 0887-6924-
dc.identifiere-issn: 1476-5551-
dc.identifier.citationLeukemia 25: 718- 722 (2011)-
dc.identifier.urihttp://hdl.handle.net/10261/59816-
dc.description.abstractChronic lymphocytic leukemia (CLL) is the most common type of leukemia in the Western world. The disease is typically diagnosed in adults >40 years old, who show an expansion (>5 × 109 cells per l) of clonal B-cells with a unique CD5+, CD23+, B-cell receptor (BCR)low immunophenotype in peripheral blood (PB) and bone marrow, frequently in association with involvement of other lymphoid tissues, disease symptoms and a heterogeneous clinical outcome.-
dc.language.isoeng-
dc.publisherNature Publishing Group-
dc.rightsclosedAccess-
dc.titleCLL-like B-lymphocytes are systematically present at very low numbers in peripheral blood of healthy adults-
dc.typeartículo-
dc.identifier.doi10.1038/leu.2010.305-
dc.date.updated2012-11-08T10:50:37Z-
dc.description.versionPeer Reviewed-
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairetypeartículo-
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