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dc.contributor.authorDasilva, Noelia-
dc.contributor.authorDíez, Paula-
dc.contributor.authorMatarraz, Sergio-
dc.contributor.authorGonzález González, María-
dc.contributor.authorParadinas, Sara-
dc.contributor.authorOrfao, Alberto-
dc.contributor.authorFuentes, Manuel-
dc.date.accessioned2012-11-06T10:44:36Z-
dc.date.available2012-11-06T10:44:36Z-
dc.date.issued2012-
dc.identifierdoi: 10.3390/s120202284-
dc.identifierissn: 1424-8220-
dc.identifier.citationSensors 12(2): 2284-2308 (2012)-
dc.identifier.urihttp://hdl.handle.net/10261/59538-
dc.descriptionThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.-- This article belongs to the Special Issue Biomarkers and Nanosensors: New Approaches for Biology and Medicine.-
dc.description.abstractDuring the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and applications in biomarker discovery. In addition, several disease biomarkers are shown in order to display the clinical importance of the improvement of sensitivity and selectivity by using nanoproteomics approaches as novel sensors. © 2012 by the authors.-
dc.description.sponsorshipWe gratefully acknowledge financial support from the Carlos III Health Institute of Spain (ISCIII, FIS PI081884) and JCYL-SAN10. María González-González is supported by a ISCIII FIS08/00721 PhD scholarship. Sara Paradinas is supported by a JCYL-EDU/1468/2008 PhD scholarship.-
dc.description.sponsorshipWe acknowledge support by the CSIC Open Access Publication Initiative through its Unit of Information Resources for Research (URICI)-
dc.language.isoeng-
dc.publisherMultidisciplinary Digital Publishing Institute-
dc.relation.isversionofPublisher’s version-
dc.rightsopenAccess-
dc.titleBiomarker discovery by novel sensors based on nanoproteomics approaches-
dc.typeArtículo-
dc.identifier.doi10.3390/s120202284-
dc.relation.publisherversionhttp://dx.doi.org/10.3390/s120202284-
dc.date.updated2012-11-06T10:44:37Z-
dc.description.versionPeer Reviewed-
dc.rights.licensehttp://creativecommons.org/licenses/by/3.0/-
dc.contributor.funderJunta de Castilla y León-
dc.contributor.funderInstituto de Salud Carlos III-
dc.contributor.funderInstituto de Salud Carlos III-
dc.contributor.funderConsejo Superior de Investigaciones Científicas (España)-
dc.relation.csic-
dc.identifier.funderhttp://dx.doi.org/10.13039/501100004587es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100003339es_ES
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