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Biomarker discovery by novel sensors based on nanoproteomics approaches

AutorDasilva, Noelia; Díez, Paula; Matarraz, Sergio; González González, María; Paradinas, Sara; Orfao, Alberto ; Fuentes, Manuel
Fecha de publicación2012
EditorMultidisciplinary Digital Publishing Institute
CitaciónSensors 12(2): 2284-2308 (2012)
ResumenDuring the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and applications in biomarker discovery. In addition, several disease biomarkers are shown in order to display the clinical importance of the improvement of sensitivity and selectivity by using nanoproteomics approaches as novel sensors. © 2012 by the authors.
DescripciónThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license.-- This article belongs to the Special Issue Biomarkers and Nanosensors: New Approaches for Biology and Medicine.
Versión del editorhttp://dx.doi.org/10.3390/s120202284
URIhttp://hdl.handle.net/10261/59538
DOI10.3390/s120202284
Identificadoresdoi: 10.3390/s120202284
issn: 1424-8220
Aparece en las colecciones: (IBMCC) Artículos
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