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Advances in Ewing's sarcoma research: Where are we now and what lies ahead?

AuthorsOrdóñez, José Luis ; Osuna, Daniel; Herrero-Martín, David; Álava, Enrique de ; Madoz-Gúrpide, Juan
Issue Date2009
PublisherAmerican Association for Cancer Research
CitationCancer Research 69(18): 7140-7150 (2009)
AbstractEwing's sarcoma family tumors (EFT) are characterized by specific chromosomal translocations, which lead to EWS/ETS transcription factors.Elucidation of EWS/ETS target gene networks within the context of other signaling pathways, together with the identification of the initiating cell, and the development of genetically engineered mice will hopefully lead to biology-based therapeutic strategies for these tumors. 2009 American Association for Cancer Research.
Identifiersdoi: 10.1158/0008-5472.CAN-08-4041
issn: 0008-5472
e-issn: 1538-7445
Appears in Collections:(IBMCC) Artículos
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