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Dose-response relationships. A model for describing interactions, and its application to the combined effect of nisin and lactic acid on Leuconostoc mesenteroides

AuthorsLópez Cabo, Marta ; Murado García, Miguel Anxo ; González Fernández, Pilar ; Pastoriza, Laura
Issue Date2000
PublisherBlackwell Publishing
CitationJournal of Applied Microbiology 88(5): 756-763 (2000)
AbstractAs well as producing bacteriocins, many lactic bacteria produce other potentially toxic compounds or growth inhibitors, especially lactic acid, which may interfere in the assays commonly used to quantify these peptides. A systematic set of modifications is proposed which, when applied to the logistical equation, enable it to describe the combined (but not additive) effects of two or more active principles. The general model thus derived is applied to the interaction of nisin and lactic acid on Leuconostoc mesenteroides.
Description8 páginas, 7 figuras, 2 tablas
Publisher version (URL)http://dx.doi.org/10.1046/j.1365-2672.2000.01010.x
Appears in Collections:(IIM) Artículos
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