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http://hdl.handle.net/10261/56974
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Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | López-Lluch, Guillermo | - |
dc.contributor.author | Rodríguez-Aguilera, Juan Carlos | - |
dc.contributor.author | Santos-Ocaña, Carlos | - |
dc.contributor.author | Navas, Plácido | - |
dc.date.accessioned | 2012-10-01T09:26:32Z | - |
dc.date.available | 2012-10-01T09:26:32Z | - |
dc.date.issued | 2011 | - |
dc.identifier | doi: 10.1016/j.mad.2010.02.003 | - |
dc.identifier | issn: 0047-6374 | - |
dc.identifier.citation | Mechanisms of Ageing and Development 131(4): 225- 235 (2011) | - |
dc.identifier.uri | http://hdl.handle.net/10261/56974 | - |
dc.description.abstract | Coenzyme Q (Q) is a key component for bioenergetics and antioxidant protection in the cell. During the last years, research on diseases linked to Q-deficiency has highlighted the essential role of this lipid in cell physiology. Q levels are also affected during aging and neurodegenerative diseases. Therefore, therapies based on dietary supplementation with Q must be considered in cases of Q deficiency such as in aging. However, the low bioavailability of dietary Q for muscle and brain obligates to design new mechanisms to increase the uptake of this compound in these tissues. In the present review we show a complete picture of the different functions of Q in cell physiology and their relationship to age and agerelated diseases. Furthermore, we describe the problems associated with dietary Q uptake and the mechanisms currently used to increase its uptake or even its biosynthesis in cells. Strategies to increase Q levels in tissues are indicated. | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier | - |
dc.rights | closedAccess | - |
dc.title | Is coenzyme Q a key factor in aging? | - |
dc.type | artículo | - |
dc.identifier.doi | 10.1016/j.mad.2010.02.003 | - |
dc.date.updated | 2012-10-01T09:26:32Z | - |
dc.description.version | Peer Reviewed | - |
dc.relation.csic | Sí | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
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