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Closed Access item Large Conjugative Plasmids from Clinical Strains of Salmonella enterica Serovar Virchow Contain a Class 2 Integron in Addition to Class 1 Integrons and Several Non-Integron-Associated Drug Resistance Determinants

Authors:Rodríguez, Irene
Rodicio, M. Rosario
Mendoza, M. Carmen
Martín, M. Cruz
Keywords:Infection, Bacteriosis, Bacteria, Enterobacteriaceae, Treatment resistance, Integron, Serotype, Salmonellosis, Salmonella, Strain, Plasmid
Issue Date:Apr-2006
Publisher:American Society for Microbiology
Citation:Antimicrobial Agents and Chemotherapy 50: 1603-1607 (2006)
Abstract:Two large conjugative resistance (R) plasmids from clinical strains of Salmonella enterica serovar Virchow carried a class 2 integron with the 5' conserved sequence (5'CS)-dfrA1-sat1-aadA1-3'CS gene array, which is associated with defective Tn7 transposons. In addition, each contained a different class 1 integron (with 5'CS-aadA1-3'CS or 5'CS-sat-smr-aadA1-3'CS gene arrays) linked to Tn21-Tn9 sequences, and several non-integron-associated R determinants. An intact copy of Tn7 (including the class 2 integron) was present in the chromosome of each strain.
Description:Final full-text version of the paper available at: http://dx.doi.org/10.1128/AAC.50.4.1603-1607.2006.
Publisher version (URL):http://dx.doi.org/10.1128/AAC.50.4.1603-1607.2006
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