Por favor, use este identificador para citar o enlazar a este item:
http://hdl.handle.net/10261/55233
COMPARTIR / EXPORTAR:
SHARE CORE BASE | |
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Guxens, Mónica | - |
dc.contributor.author | Fitó, Montserrat | - |
dc.contributor.author | Martínez-González, Miguel Ángel | - |
dc.contributor.author | Salas-Salvadó, Jordi | - |
dc.contributor.author | Estruch, Ramón | - |
dc.contributor.author | Vinyoles, Ernest | - |
dc.contributor.author | Fiol, Miquel | - |
dc.contributor.author | Corella, Dolores | - |
dc.contributor.author | Arós, Fernando | - |
dc.contributor.author | Gómez-Gracia, Enrique | - |
dc.contributor.author | Ruiz-Gutiérrez, Valentina | - |
dc.contributor.author | Lapetra, José | - |
dc.contributor.author | Ros, Emilio | - |
dc.contributor.author | Vila, Joan | - |
dc.contributor.author | Covas, María Isabel | - |
dc.date.accessioned | 2012-08-29T11:51:59Z | - |
dc.date.available | 2012-08-29T11:51:59Z | - |
dc.date.issued | 2009-01 | - |
dc.identifier.citation | American Journal of Hypertension 22(1): 68-73 (2009) | es_ES |
dc.identifier.issn | 0895-7061 | - |
dc.identifier.other | PMID: 19008862 | - |
dc.identifier.uri | http://hdl.handle.net/10261/55233 | - |
dc.description.abstract | BACKGROUND: In elderly individuals, hypertension is a main risk factor for cardiovascular disease and oxidative damage is increased. Our aim was to assess the relationship between the degree of in vivo low-density lipoprotein (oxLDL) oxidation and the hypertensive status in a elderly population at high cardiovascular risk. METHODS: Cross-sectional study with baseline data from the PREDIMED (PREvención con DIeta MEDiterránea) trial, an intervention study directed at testing the efficacy of the Mediterranean diet on the primary prevention of cardiovascular disease. Participants were 1,130 subjects at high cardiovascular risk aged 55-80. At baseline, in vivo circulating oxLDL was measured, and stages of hypertension determined according to the USA Joint National Committee guidelines. RESULTS: A positive relationship between in vivo oxLDL and systolic and diastolic blood pressure (DBP) was observed after adjusting for confounding factors (P < 0.05). OxLDL concentrations increased in a linear manner from low to high hypertensive stages (P < 0.05). CONCLUSIONS: Elderly individuals at high cardiovascular risk showed higher levels of circulating oxLDL when their hypertensive status increased. This fact identifies the hypertensive elderly population as a target for antioxidant preventive measures. | es_ES |
dc.description.sponsorship | This study was funded by the Spanish Ministry of Health (Networks G03/140, RD06/0045 and research grants PI040233, PI070240, and CP06/00100 of the Instituto de Salud Carlos III). The CIBER Fisiopatología de la Obesidad y Nutrition and the CIBER Epidemiología y Salud Pública are an initiative of the Instituto de Salud Carlos III. We thank the Fundación Patrimonio Comunal Olivarero and Hojiblanca SA, California Walnut Commission, Borges SA, and Morella Nuts SA for donating the olive oil, walnuts, almonds, and hazelnuts, respectively. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Nature Publishing Group | es_ES |
dc.rights | closedAccess | es_ES |
dc.subject | Coronary disease | es_ES |
dc.subject | Hypertension | es_ES |
dc.subject | Lipid peroxidation | es_ES |
dc.subject | Lypoproteins | es_ES |
dc.subject | Oxidative stress | es_ES |
dc.title | Hypertensive Status and Lipoprotein Oxidation in an Elderly Population at High Cardiovascular Risk | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1038/ajh.2008.313 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1038/ajh.2008.313 | es_ES |
dc.identifier.e-issn | 1941-7225 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.languageiso639-1 | en | - |
item.fulltext | No Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.openairetype | artículo | - |
Aparece en las colecciones: | (IG) Artículos |
CORE Recommender
SCOPUSTM
Citations
20
checked on 24-abr-2024
WEB OF SCIENCETM
Citations
17
checked on 28-feb-2024
Page view(s)
342
checked on 24-abr-2024
Google ScholarTM
Check
Altmetric
Altmetric
NOTA: Los ítems de Digital.CSIC están protegidos por copyright, con todos los derechos reservados, a menos que se indique lo contrario.