English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/54944
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:


Evolution of a multifunctional gene: The warm temperature acclimation protein Wap65 in the European seabass Dicentrarchus labrax

AuthorsSarropoulou, Elena; Fernandes, Jorge M. O.; Mitter, Karin; Magoulas, Antonios; Mulero, Victoriano; Sepulcre, Pilar; Figueras Huerta, Antonio ; Novoa, Beatriz ; Kotoulas, Georgios
Gene evolution
Positive selection
Differential expression
Issue Date2010
CitationMolecular Phylogenetics and Evolution 55(2): 640-649 (2010)
AbstractThe warm temperature acclimation protein Wap65 has been shown to be involved in temperature acclimation, in immune response as well as in development. In teleosts, two types of Wap65 proteins, Wap65-1 and Wap65-2 are found, both acting as a multifunctional agent in several biological processes. In the present study we identified both transcripts Wap65-1 and Wap65-2 for the European seabass (Dicentrarchus labrax), examined their evolutionary rate and performed selection tests. The two paralogues were shown to be under moderate positive selection indicating their evolutionary adaptation. This functional diversification was further explored through expression studies. Both transcripts were differentially expressed during development as well as in various tissues and pathogen challenges, showing that Wap65-1 and Wap65-2 have evolved diverse functions. These results direct to the hypothesis that Wap65 proteins may, similarly to heat-shock proteins, have a general role in cell physiology
Description10 páginas, 5 figuras, 2 tablas
Publisher version (URL)http://dx.doi.org/10.1016/j.ympev.2009.10.001
Appears in Collections:(IIM) Artículos
Files in This Item:
There are no files associated with this item.
Show full item record
Review this work

Related articles:

WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.