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Closed Access item An epigenetic mark that protects the epithelial phenotype in health and disease

Authors:Heredia, Fabiana
Nieto, M. Ángela
Issue Date:2011
Publisher:Cell Press
Citation:Cell Stem Cell 8(5): 462-463 (2011)
Abstract:Epithelial plasticity is crucial during embryonic development and progression of carcinomas. In this issue, Abell et al. (2011) show that acetylation on histones H2A/H2B prevents epithelial cells from undergoing epithelial-to-mesenchymal transition (EMT). Their findings also suggest that under conditions where EMT and stemness coexist, they can be independently regulated. © 2011 Elsevier Inc.
Identifiers:doi: 10.1016/j.stem.2011.04.011
issn: 1934-5909
e-issn: 1875-9777
Appears in Collections:(IN) Artículos

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