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Closed Access item Position correction with depth of interaction information for a small animal PET system

Authors:Carles, Montserrat
Lerche, Christoph W.
Sánchez, Filomeno J.
Mora, Francisco José
Benlloch Baviera, José María
Issue Date:2011
Publisher:Elsevier
Citation:NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT 648: S176-S180 (2011)
Abstract:In this work we study the effects on the spatial resolution when depth of interaction (DOI) information is included in the parameterization of the line of response (LOR) for a small animal positron emission tomography (PET) system. One of the most important degrading factors for PET is the parallax error introduced in systems that do not provide DOI information of the recorded γ-rays. Our group has designed a simple and inexpensive method for DOI determination in continuous scintillation crystals. This method is based, on one hand, in the correlation between the scintillation light distribution width in monolithic crystals and the DOI, and, on the other hand, on a small modification of the widely applied charge dividing circuits (CDR). In this work we present a new system calibration that includes the DOI information, and also the development of the correction equations that relates the LOR without and with DOI information. We report the results obtained for different measurements along the transaxial field of view (FOV) and the image quality enhancement achieved specially at the edge of the FOV. © 2010 Elsevier B.V. All rights reserved.
URI:http://hdl.handle.net/10261/52138
Identifiers:doi: 10.1016/j.nima.2010.11.192
issn: 0168-9002
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