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Title

Dietary fiber, gut peptides, and adipocytokines

AuthorsSánchez, David ; Miguel, Marta ; Aleixandre, Amaya
Issue Date2012
PublisherMary Ann Liebert
CitationJournal of Medicinal Food 15(3): 223-230 (2012)
AbstractThe consumption of dietary fiber (DF) has increased since it was related to the prevention of a range of illnesses and pathological conditions. DF can modify some gut hormones that regulate satiety and energy intake, thus also affecting lipid metabolism and energy expenditure. Among these gut hormones are ghrelin, glucagon-like peptide 1, peptide YY, and cholecystokinin. Adipose tissue is known to express and secrete a variety of products known as >adipocytokines,> which are also affected by DF. Some of the most relevant adipocytokines include adiponectin, leptin, tumor necrosis factor-α, and interleukin-6. The release of adipocytokines, by either adipocytes or macrophage-infiltrated adipose tissue, leads to a chronic subinflammatory state that could play a central role in the development of insulin resistance and type 2 diabetes, therefore increasing the risk of cardiovascular disease associated with obesity. DF modulation of these molecules could also have positive effects on obesity, insulin resistance, and hyperlipidemia. This review is focused on the effects of DF on the above-mentioned gut peptides and adipocytokines. © Copyright 2012, Mary Ann Liebert, Inc. and Korean Society of Food Science and Nutrition 2012.
Publisher version (URL)http://dx.doi.org/10.1089/jmf.2011.0072
URIhttp://hdl.handle.net/10261/51636
DOI10.1089/jmf.2011.0072
Identifiersdoi: 10.1089/jmf.2011.0072
issn: 1096-620X
e-issn: 1557-7600
Appears in Collections:(CIAL) Artículos
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