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Open Access item Inorganic pyrophosphatase defects lead to cell cycle arrest and autophagic cell death through NAD+-Depletion in fermenting yeast

Authors:Serrano, Gloria
Hernández, A.
López-Lluch, Guillermo
Pérez-Castiñeira, J. R.
Navas, Plácido
Serrano, A.
Keywords:Pyrophosphatase, Cell cycle, DNA, RNA, Saccharomyces cerevisiae proteins
Issue Date:12-Dec-2011
Publisher:Sociedad Española de Biología Celular
Citation:Libro de resúmenes : 162 (2011)
Abstract:Pyrophosphate removal is essential for several central biosynthetic reactions to proceed in the appropriate direction, e.g. NAD+, DNA, RNA synthesis or tRNA amino acylation. Defects in the genes encoding the pyrophosphate hydrolytic enzymes are considered inviable, although its exact nature has not been studied at the cell physiology level.
Description:1 página. XIV Congresos de la Sociedad Española de Biología Celular (Málaga, 12-15 de diciembre, 2011).
Publisher version (URL):http://www.congresosebc2011.uma.es/documentos/LibroAbstractsSEBC2011.pdf
Appears in Collections:(IBVF) Comunicaciones congresos

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