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Título : Inorganic pyrophosphatase defects lead to cell cycle arrest and autophagic cell death through NAD+-Depletion in fermenting yeast
Autor : Serrano, Gloria, Hernández, Agustín, López-Lluch, Guillermo, Pérez-Castiñeira, J. R., Navas, Plácido, Serrano, Aurelio
Palabras clave : Pyrophosphatase
Cell cycle
Saccharomyces cerevisiae proteins
Fecha de publicación : 12-Dec-2011
Editor: Sociedad Española de Biología Celular
Citación : Libro de resúmenes : 162 (2011)
Resumen: Pyrophosphate removal is essential for several central biosynthetic reactions to proceed in the appropriate direction, e.g. NAD+, DNA, RNA synthesis or tRNA amino acylation. Defects in the genes encoding the pyrophosphate hydrolytic enzymes are considered inviable, although its exact nature has not been studied at the cell physiology level.
Descripción : 1 página. XIV Congresos de la Sociedad Española de Biología Celular (Málaga, 12-15 de diciembre, 2011).
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Appears in Collections:(IBVF) Comunicaciones congresos

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