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Title: Inorganic pyrophosphatase defects lead to cell cycle arrest and autophagic cell death through NAD+-Depletion in fermenting yeast
Authors: Serrano, Gloria, Hernández, Agustín, López-Lluch, Guillermo, Pérez-Castiñeira, J. R., Navas, Plácido, Serrano, Aurelio
Keywords: Pyrophosphatase
Cell cycle
Saccharomyces cerevisiae proteins
Issue Date: 12-Dec-2011
Publisher: Sociedad Española de Biología Celular
Abstract: Pyrophosphate removal is essential for several central biosynthetic reactions to proceed in the appropriate direction, e.g. NAD+, DNA, RNA synthesis or tRNA amino acylation. Defects in the genes encoding the pyrophosphate hydrolytic enzymes are considered inviable, although its exact nature has not been studied at the cell physiology level.
Description: 1 página. XIV Congresos de la Sociedad Española de Biología Celular (Málaga, 12-15 de diciembre, 2011).
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Citation: Libro de resúmenes : 162 (2011)
Appears in Collections:(IBVF) Comunicaciones congresos

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