Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/47868
Título : Cyclobutane serine amino acid derivatives as 5-hydroxyproline precursors
Autor : Pérez-Fernández, Marta, Avenoza, Alberto, Busto, Jesús H., Peregrina, Jesús M., Rodríguez, Fernando
Palabras clave : 5-Hydroxyproline
Cyclobutane derivatives
Michael addition
Wittig reaction
Fecha de publicación : 10-Jun-2009
Citación : ARKIVOC - Online Journal of Organic Chemistry 191-2002 (2009)
Resumen: The synthesis of the 5-hydroxyproline derivatives 3a and 3b using cyclobutane serine analogs 1 and 2 as starting materials is reported. This process occurs with moderate cis/trans selectivity. A mechanism for this reaction is also proposed. Cyclobutane serine analog 1 was tested in tandem Michael and Wittig-like reactions, providing some evidence of the mechanism proposed.
Descripción : This article is dedicated to Professor Benito Alcaide on the occasion of his 60 th birthday
Versión del editor: http://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/2010/3/
URI : http://hdl.handle.net/10261/47868
ISSN: 1551-7004
Appears in Collections:(ICVV) Artículos

Files in This Item:
File Description SizeFormat 
BA-3955EP published mainmanuscript.pdf156,47 kBAdobe PDFView/Open
Show full item record
 
CSIC SFX LinksSFX Query

Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.