English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/47611
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:
DC FieldValueLanguage
dc.contributor.authorOrtuño, Jordi-
dc.contributor.authorCovas, María Isabel-
dc.contributor.authorFarré, Magí-
dc.contributor.authorPujadas, Mitona-
dc.contributor.authorFitó, Montserrat-
dc.contributor.authorKhymenets, Olha-
dc.contributor.authorAndrés-Lacueva, Cristina-
dc.contributor.authorRoset, Pere N.-
dc.contributor.authorJoglar Tamargo, Jesús-
dc.contributor.authorLamuela-Raventós, Rosa M.-
dc.contributor.authorTorre, Rafael de la-
dc.date.accessioned2012-03-28T08:28:04Z-
dc.date.available2012-03-28T08:28:04Z-
dc.date.issued2010-
dc.identifier.citationFood Chemistryes_ES
dc.identifier.issn0308-8146-
dc.identifier.urihttp://hdl.handle.net/10261/47611-
dc.description.abstractThe pharmacokinetics of resveratrol in 11 healthy male volunteers has been assessed in a randomized, crossover, controlled clinical trial after the administration of three grape products: red wine (250 mL), grape juice (1/L), or tablets (red wine extracts enriched with trans-resveratrol). Doses of trans-resveratrol independently of the product administered, were about 14 μg/kg. Biological samples were collected and analysed by capillary gas chromatography–mass spectrometry. cis-Resveratrol, trans-resveratrol and dihydroresveratrol were determined in plasma and urine. Plasma concentration of trans-resveratrol after hydrolysis increased as a response to all grape products and that of cis-resveratrol after wine and grape juice. Free forms of these phenolic compounds were deemed undetectable in plasma. Despite similar trans-resveratrol doses being administered, its bioavailability from wine and grape juice was 6-fold higher, than that from tablets. Resveratrol was better absorbed from natural grape products than from tablets, pointing out the importance of the matrix in its bioavailability.es_ES
dc.language.isoenges_ES
dc.publisherElsevieres_ES
dc.rightsclosedAccesses_ES
dc.subjectResveratroles_ES
dc.subjectGrape productses_ES
dc.subjectWinees_ES
dc.subjectGrape juicees_ES
dc.subjectResveratrol dispositiones_ES
dc.titleMatrix effects on the bioavailability of resveratrol in humanses_ES
dc.typeArtículoes_ES
dc.identifier.doi10.1016/j.foodchem.2009.11.032-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.foodchem.2009.11.032es_ES
Appears in Collections:(IQAC) Artículos
Files in This Item:
There are no files associated with this item.
Show simple item record
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.