English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/44370
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Novel sulfamide analogs of oleoylethanolamide showing in vivo satiety inducing actions and PPAR alpha activation

AuthorsCano, Carolina ; Pavón, Javier; Serrano, Antonia; Goya, Pilar ; Páez, Juan A. ; Rodriguez de Fonseca, Fernando; Macías-González, Manuel
KeywordsOleoylethanolamide
PPARα
Issue Date2007
PublisherAmerican Chemical Society
CitationJournal of Medicinal Chemistry 50 : 389-393 (2007)
AbstractLong chain saturated and unsaturated alkyl sulfamide and propyl sulfamide derivatives, analogs of oleoylethanolamide, have been synthesized and evaluated in ViVo and in Vitro as peroxisome proliferator activated receptor alpha (PPARR) activators. Additionally, the anorexic effects of the new compounds have been studied in ViVo in food-deprived rats. Among the active compounds N-octadecyl-N¢-propylsulfamide (7) has been identified as a potent hypolipidemic compound, a potent feeding suppressant, and a concentrationdependent activator of PPARR.
Publisher version (URL)http://dx.doi.org/10.1021/jm0601102
URIhttp://hdl.handle.net/10261/44370
DOI10.1021/jm0601102
ISSN0022-2623
Appears in Collections:(IQM) Artículos
Files in This Item:
There are no files associated with this item.
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.