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| Título: | Recombination gives a new insight in the effective population size and the history of the Old World human populations |
Autor: | Melé, Marta CSIC ORCID; Pybus, Marc CSIC ORCID; Comas, David CSIC ORCID ; Calafell, Francesc CSIC ORCID ; Bertranpetit, Jaume CSIC ORCID | Palabras clave: | Recombination Effective population size Out of Africa |
Fecha de publicación: | 2012 | Editor: | Oxford University Press | Citación: | Molecular Biology and Evolution 29(1): 25-30 (2011) | Resumen: | The information left by recombination in our genomes can be used to make inferences on our recent evolutionary history. Specifically, the number of past recombination events in a population sample is a function of its effective population size (Ne). We have applied a method, IRiS, to detect specific past recombination events in 30 Old World populations to infer their Ne. We have found that Sub-Saharan African populations have an Ne that is ∼ 4 times greater than those of non-African populations and that outside of Africa, South Asian populations had the largest Ne. We also observe that the patterns of recombinational diversity of these populations correlate with distance out of Africa if that distance is measured along a path crossing South Arabia. No such correlation is found through a Sinai route, suggesting that anatomically modern humans first left Africa through the Bab-el-Mandeb strait rather than through present Egypt. | Descripción: | Melé, Marta et al.-- The Genographic Consortium | Versión del editor: | http://dx.doi.org/10.1093/molbev/msr213 | URI: | http://hdl.handle.net/10261/43355 | DOI: | 10.1093/molbev/msr213 | ISSN: | 0737-4038 | E-ISSN: | 1537-1719 |
| Aparece en las colecciones: | (IBE) Artículos |
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