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Open Access item Substituted 5-IMINO-1,2,4-THIADIAZOLES that can be used to treat neurodegenerative diseases

Other Titles:1,2,4-TIADIZOLES-5-IMINO sustituidos útiles en el tratamiento de enfermedades neurodegenerativas
Authors:Martínez, Ana
Gil, Carmen
Palomo Ruiz, Valle
Pérez Fernández, Daniel Ignacio
Pérez Martín, María Concepción
Pérez Castillo, Ana
Loza García, María Isabel
Cadavid, María Isabel
Brea Floriani, José
Issue Date:7-Apr-2011
Citation:WO2011039403 A1
Abstract:[ES] La presente invención se refiere al uso de una familia amplia de 1,2,4-tiadiazoles-5-imino sustituidos como potenciales nuevos fármacos para el tratamiento de enfermedades donde la inhibición de PDE7 es relevante, en especial
[EN] The present invention relates to the use of a broad family of substituted 5-imino-l,2,4-thiadiazoles as potential novel drugs for treating diseases in which PDE7 inhibition is relevant, especially inflammatory, autoimmune and neurodegenerative diseases. Furthermore, a description is given of compounds of the substituted 5-imino-l ,2,4-thiadiazole family and also the method for the production thereof, said substituted 5-imino-l,2,4-thiadiazoles possibly having a broad sphere of use as drugs or candidate drugs. Therefore, a frrst aspect ofthe present invention relates to a compound offormula (l).
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