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Endogenous synthesis of rumenic acid in the mammary gland of dairy ewes

AuthorsToral, Pablo G. ; Bichi, Elena ; Hervás, Gonzalo ; Gómez-Cortés, Pilar ; Fuente, Miguel Ángel de la ; Juárez, Manuela ; Frutos, Pilar
Issue Date2011
PublisherCambridge University Press
CitationAdvances in Animal Biosciences 2(2): 568 (2011)
8th International Symposium on the Nutrition of Herbivores : 568 (2011)
AbstractIn ruminants, the enzyme Δ9-desaturase has a key role in the synthesis of milk fatty acids (FA) through the introduction of a cis double bond between carbon atoms 9 and l0 (Palmquist et al., 2005). In recent years. the study of Δ9-desaturase activity has had a renewed interest, after Griinari et al. (2000) demonstrated that endogenous synthesis in the mammary gland of cows is the major source of the potentially health-promotin c9t11-18:2 (rumenic acid, a conjugated linoleic acid isomer) found in milk. It is now well known that this occurs via desaturation of t11-18:1 of rumen origin, but the number of studies quantifying the proportion of c9t11-18:2 synthesized endogenously is still limited in ruminants (Palmquist et al.,2005).Thus, in sheep, there is no information on this subject, despite the high levels of c9t11 -18:2 often found in ovine milk, which might be related with a higher Δ9-desaturase activity in this species(Tsiplakou et al., 2009). The aim of this study was therefore to examine the endogenous synthesis of c9t11-18:2 in the mammary gland of dairy ewes, via the administration of sterculic acid, a cyclopropenoic FA that specifically inhibits the Δ9-desaturase system (Gomez et al.,2003).
Description1 página, 1 table.-- Trabajo presentado al: 8th International Symposium on the Nutrition of Herbivores (Aberystwyth, Reino Unido, 6 al 9 de septiembre de 2011).
Publisher version (URL)http://www.isnh8.org/
Appears in Collections:(IGM) Comunicaciones congresos
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