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Título : Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity
Autor : Esteban, J. A.
Palabras clave : AMPA-type glutamate receptors
Long-term depression (LTD)
Long-term potentiation (LTP)
Synaptic function
Fecha de publicación : 2008
Editor: Springer
Citación : Synaptic Plasticity and the Mechanism of Alzheimer's Disease Research and Perspectives in Alzheimer’s Disease, 19-35 (2008)
Resumen: AMPA-type glutamate receptors are among the most dynamic components of excitatory synapses. Their regulated addition and removal from synapses lead to long-lasting forms of synaptic plasticity, known as long-term potentiation (LTP) and long-term depression (LTD). In addition, AMPA receptors (AMPARs) reach their synaptic targets after a complicated journey involvingmultiple transport steps through different membrane compartments. This chapter summarizes our current knowledge of the trafficking pathways of AMPARs and their relation to synaptic function and plasticity.
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ISBN : 978-3-540-76329-1
Appears in Collections:(CBM) Libros y Partes de Libros

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