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|Title:||Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity|
|Authors:||Esteban, José A.|
|Keywords:||AMPA-type glutamate receptors|
Long-term depression (LTD)
Long-term potentiation (LTP)
|Citation:||Synaptic Plasticity and the Mechanism of Alzheimer's Disease Research and Perspectives in Alzheimer’s Disease, 19-35 (2008)|
|Abstract:||AMPA-type glutamate receptors are among the most dynamic components of excitatory synapses. Their regulated addition and removal from synapses lead to long-lasting forms of synaptic plasticity, known as long-term potentiation (LTP) and long-term depression (LTD). In addition, AMPA receptors (AMPARs) reach their synaptic targets after a complicated journey involvingmultiple transport steps through different membrane compartments. This chapter summarizes our current knowledge of the trafficking pathways of AMPARs and their relation to synaptic function and plasticity.|
|Publisher version (URL):||http://dx.doi.org/10.1007/978-3-540-76330-7|
|Appears in Collections:||(CBM) Libros y Partes de Libros|
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