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Closed Access item Symmetrical transcription in bacteriophage φ29 DNA

Authors:Barthelemy, Isabel
Mellado, Rafael P.
Salas, Margarita
Keywords:φ29 transcription, Early promoter functions, Ttranscriptional control
Issue Date:5-May-1988
Citation:Biochimie 70((5): 605-609 (1988)
Abstract:Transcription of some early genes occurring during φ29 infection in the absence but not in the presence of chloramphenicol has been shown to depend upon the synthesis of the viral protein p4, the positive regulator of late transcription. In addition, the early promoter B1, responsible for early transcription on the late region of the φ29 genome, has been accurately mapped by nuclease S1 protection experiments. The deduced promoter sequence shares homology with that of the other early φ29 promoters previously described and with the consensus sequence of the promoters recognized by the Bacillus subtilisσ43-RNA polymerase.
Publisher version (URL):http://dx.doi.org/10.1016/0300-9084(88)90243-X
Appears in Collections:(CBM) Artículos

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