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http://hdl.handle.net/10261/39397
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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Nuez, Beatriz | - |
dc.contributor.author | Rojo, Fernando | - |
dc.contributor.author | Barthelemy, Isabel | - |
dc.contributor.author | Salas, Margarita | - |
dc.date.accessioned | 2011-09-12T09:17:01Z | - |
dc.date.available | 2011-09-12T09:17:01Z | - |
dc.date.issued | 1991 | - |
dc.identifier.citation | Nucleic Acids Research 19(9): 2337-2342 (1991) | es_ES |
dc.identifier.issn | 0305-1048 | - |
dc.identifier.uri | http://hdl.handle.net/10261/39397 | - |
dc.description.abstract | requires the transcriptional activator protein p4. This activator binds to a region of the late A3 promoter spanning nucleotides -56 to -102 relative to the transcription start site, generating a strong bendlngTIn the DNA. In this work the target sequences recognized by protein p4 In the phage φ29 late A3 promoter have been characterized. The binding of protein p4 to derivatives of the late A3 promoter harbouring deletions in the protein p4 binding site has been studied. When protein p4 recognition sequences were altered, the activator could only bind to the promoter in the presence of RNA polymerase. This strong cooperatlvtty in the binding of protein p4 and RNA polymerase to the promoter suggests the presence of direct protein-protein contacts between them. | es_ES |
dc.description.sponsorship | This investigation was aided by research grants from the National Institutes of Health (5R01 GM27242-1 1) and Direcci6n General de Investigaci6n Cientifica y Tecnica (PB87 0323), and an institutional grant from Fundaci6n Ram6n Areces. B.N. was holder of a pre-doctoral F.P.I. fellowship from M.E.C., and F.R. and I.B. of postdoctoral fellowships from C.S.I.C. | - |
dc.language.iso | eng | es_ES |
dc.publisher | Oxford University Press | es_ES |
dc.rights | openAccess | es_ES |
dc.title | Identification of the sequences recognized by phage ϕ29 transcriptional activator: possible interaction between the activator and the RNA polymerase | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1093/nar/19.9.2337 | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1093/nar/19.9.2337 | es_ES |
dc.identifier.e-issn | 1362-4962 | - |
dc.contributor.funder | National Institutes of Health (US) | - |
dc.contributor.funder | Ministerio de Economía y Competitividad (España) | - |
dc.contributor.funder | Fundación Ramón Areces | - |
dc.contributor.funder | Ministerio de Educación y Ciencia (España) | - |
dc.contributor.funder | Consejo Superior de Investigaciones Científicas (España) | - |
dc.identifier.funder | http://dx.doi.org/10.13039/100000002 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003329 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/100008054 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100003339 | es_ES |
dc.identifier.pmid | 1904153 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.grantfulltext | open | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
item.languageiso639-1 | en | - |
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