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Closed Access item Interaction of the bacteriophage φ29 connector protein with the viral DNA

Authors:Herranz, Lucía
Salas, Margarita
Carrascosa, José L.
Issue Date:Nov-1986
Publisher:Elsevier
Citation:Virology 155(1): 289-292 (1986)
Abstract:The protein that forms the connector of phage φ29, p10, binds to DNA. Apparently, p10 binding is not sequence specific. Nevertheless, the presence of the terminal protein (p3) covalently attached to the ends of φ29 DNA produces a significant increase of p10 molecules bound to the DNA ends, thus suggesting a terminal protein-mediated recognition of DNA ends by the phage connector. As the p3-DNA complex is the substrate for phage φ29 DNA packaging, these results may reflect a direct implication of the phage connector in the packaging process.
Publisher version (URL):http://dx.doi.org/10.1016/0042-6822(86)90191-1
URI:http://hdl.handle.net/10261/39206
ISSN:0042-6822
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Appears in Collections:(CBM) Artículos

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