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Título : Structural basis for membrane anchorage of viral ø29 DNA during replication
Autor : Albert, Armando, Muñoz-Espín, D., Jiménez, M., Asensio, Juan Luis, Hermoso, José Miguel, Salas, Margarita, Meijer, Wilhelmus J. J.
Fecha de publicación : 30-Dec-2005
Editor: American Society for Biochemistry and Molecular Biology
Resumen: Prokaryotic DNA replication is compartmentalized at the cellular membrane. Functional and biochemical studies showed that the Bacillus subtilis phage ϕ29-encoded membrane protein p16.7 is directly involved in the organization of membrane-associated viral DNA replication. The structure of the functional domain of p16.7 in complex with DNA, presented here, reveals the multimerization mode of the protein and provides insights in the organization of the phage genome at the membrane of the infected cell.
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ISSN: 0021-9258
DOI: 10.1074/jbc.C500429200
Citación : The Journal of Biological Chemistry 280: 20730-20739 (2005)
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