Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/37646
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Título : Enantioselective Synthesis of Vicinal Halohydrins via Dynamic Kinetic Resolution
Autor : Ros, Abel, Magriz, Antonio, Dietrich, Hansjörg, Fernández, Rosario, Álvarez, Eleuterio, Lassaletta, José M.
Palabras clave : Enantioselective
Catalysts
Alpha-halo
Halohydrins
α-Halo
DKR
Fecha de publicación : 9-Dec-2005
Editor: American Chemical Society
Resumen: Expanding the scope of enantioselective catalysis via DKR, transfer hydrogenation of a variety of cyclic alpha-halo ketones was accomplished using the Noyori/Ikariya (R,R)- or (S,S)-I catalysts and either HCO(2)H/Et(3)N or HCO(2)Na/n-Bu(4)NBr in H(2)O/CH(2)Cl(2) as the hydrogen sources. Good yields of vicinal bromo-, chloro-, and fluorohydrins with excellent de and ee levels were achieved in most cases after a simple tuning of reaction conditions.
Descripción : 4 páginas, 1 figura, 1 tabla, 3 esquemas.
Versión del editor: http://dx.doi.org/10.1021/ol052821k
URI : http://hdl.handle.net/10261/37646
ISSN: 1523-7060
DOI: 10.1021/ol052821k
Citación : Organic Letters 8(1): 127-130 (2006)
Referencias: 16381584
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