English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/37645
Share/Impact:
Title: Intramolecular Benzyl Protection Delivery: A Practical Synthesis of DMDP and DGDP from d-Fructose
Authors: García Moreno, María Isabel; Aguilar Moncayo, Matilde; Ortiz-Mellet, Carmen; García-Fernández, José Manuel
Keywords: Ethers
Fructose
Imino pyranoses
Mannitol
Molecular structure
Sorbitol
Glycoside hydrolases
Stereoisomerism
Issue Date: 18-Dec-2005
Publisher: American Chemical Society
Citation: Organic Letters 8(2): 297-299 (2006)
Abstract: A two-step protection of 1,2-diols as the corresponding o-xylylene cyclic ethers, involving an intramolecular ring-closing O-benzylation reaction, has been developed to overcome the problems associated to regioselective benzylation reactions. The strategy has been applied to the high-yielding synthesis of the pyrrolidine glycosidase inhibitors DMDP and DGDP.
Description: 3 páginas, 4 esquemas.
Publisher version (URL): http://dx.doi.org/ 10.1021/ol052668u
URI: http://hdl.handle.net/10261/37645
DOI: 10.1021/ol052668u
ISSN: 1523-7060
References: 16408899
Appears in Collections:(IIQ) Artículos
Files in This Item:
There are no files associated with this item.
Show full item record
 



WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.