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Closed Access item Synthesis and anti-HIV properties of 1,2,4,6-thiatriazin-3-one 1,1-dioxide nucleosides

Authors:Ochoa, Carmen
Provencio, Rafael
Jimeno, M. Luisa
Balzarini, Jan
De Clercq, Erik
Issue Date:1998
Publisher:Taylor & Francis
Citation:Nucleosides Nucleotides Nucleic Acids 17 (5): 901-10 (1998)
Abstract:Synthesis of 1,2,4,6-thiatriazine 1,1-dioxide nucleosides is now reported for the first time. In order to know the conformation of the nucleosides, a NMR study has been carried out. Anti-HIV-1 and HIV-2 properties of the nucleosides have been tested. These compounds have not shown activity at subtoxic concentrations.
Publisher version (URL):http://dx.doi.org/10.1080/07328319808003462
URI:http://hdl.handle.net/10261/35788
ISSN:0732-8311
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Appears in Collections:(CENQUIOR) Artículos

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