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Título : Synthesis and anti-HIV properties of 1,2,4,6-thiatriazin-3-one 1,1-dioxide nucleosides
Autor : Ochoa, Carmen, Provencio, Rafael, Jimeno, M. Luisa, Balzarini, Jan, De Clercq, Erik
Fecha de publicación : 1998
Editor: Taylor & Francis
Resumen: Synthesis of 1,2,4,6-thiatriazine 1,1-dioxide nucleosides is now reported for the first time. In order to know the conformation of the nucleosides, a NMR study has been carried out. Anti-HIV-1 and HIV-2 properties of the nucleosides have been tested. These compounds have not shown activity at subtoxic concentrations.
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ISSN: 0732-8311
DOI: 10.1080/07328319808003462
Citación : Nucleosides Nucleotides Nucleic Acids 17 (5): 901-10 (1998)
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