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Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/35271
Title: A new and efficient one-pot synthesis of pyrido[2,1-f]purine-2,4-diones starting from 6-aminouracil derivatives
Authors: Pérez Pérez, María Jesús; Priego, Eva María; Jimeno, M. Luisa; Camarasa Rius, María José
Keywords: heterocycles
tricyclic compounds
Issue Date: 2002
Publisher: Thieme
Citation: Synlet 1 : 155-157 (2002)
Abstract: A convenient synthesis of pyrido[2,1-f]purine-2,4-diones is described by reaction of 6-aminouracil derivatives with N-bromosuccinimide (NBS) followed by in situ reaction with pyridine or 4-substituted pyridines. A detailed study of the reaction conditions has been performed and a mechanism involving a 5,5-dibromo derivative is proposed.
Publisher version (URL): http://dx.doi.org/10.1055/s-2002-19342
URI: http://hdl.handle.net/10261/35271
ISSN: 0936-5214
DOI: 10.1055/s-2002-19342
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