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| Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE | |
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Alonso De Diego, Sergio A. | - |
| dc.contributor.author | Gutiérrez-Rodríguez, Marta | - |
| dc.contributor.author | Pérez de Vega, M. Jesús | - |
| dc.contributor.author | Casabona, Diego | - |
| dc.contributor.author | Cativiela, Carlos | - |
| dc.contributor.author | González-Muñiz, Rosario | - |
| dc.contributor.author | Herranz, Rosario | - |
| dc.contributor.author | Cenarruzabeitia, Edurne | - |
| dc.contributor.author | Frechilla, Diana | - |
| dc.contributor.author | Río, Joaquín del | - |
| dc.contributor.author | Jimeno, M. Luisa | - |
| dc.contributor.author | García-López, M. Teresa | - |
| dc.date.accessioned | 2011-03-30T10:17:35Z | - |
| dc.date.available | 2011-03-30T10:17:35Z | - |
| dc.date.issued | 2006 | - |
| dc.identifier.citation | Bioorganic & Medicinal Chemistry Letters 16 : 1392–1396 (2006) | es_ES |
| dc.identifier.uri | http://hdl.handle.net/10261/33944 | - |
| dc.description.abstract | A suitable solid-phase approach, based on Fmoc/tBu methodology and on the use of 2-chlorotrityl resin, allowed a rapid and efficient preparation of new GPE analogues. Most of the synthesized tripeptides displayed glutamate receptor binding affinity comparable to that of GPE, but only a few derivatives showed significant neuroprotective activity. | es_ES |
| dc.description.sponsorship | This work has been supported by the Spanish Ministry of Education and Science (SAF 2003-07207-C02 and CT2004-5358), Comunidad de Madrid (GR/SAL/0850/ 2004), and UTE project FIMA. S.A.A.D.D. holds a predoctoral fellowship from the Ministry of Education for Associated Units to CSIC. D.C. thanks CSIC for a I3P Grant. | es_ES |
| dc.language.iso | eng | es_ES |
| dc.publisher | Elsevier | es_ES |
| dc.rights | closedAccess | es_ES |
| dc.subject | GPE analogues | es_ES |
| dc.subject | Solid-phase synthesis | es_ES |
| dc.subject | Neuroprotective activity | es_ES |
| dc.title | New Gly-Pro-Glu (GPE) analogues: Expedite solid-phase synthesis and biological activity | es_ES |
| dc.type | artículo | es_ES |
| dc.identifier.doi | 10.1016/j.bmcl.2005.11.040 | - |
| dc.description.peerreviewed | Peer reviewed | es_ES |
| dc.relation.publisherversion | http://dx.doi.org/10.1016/j.bmcl.2005.11.040 | es_ES |
| dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
| item.openairetype | artículo | - |
| item.grantfulltext | none | - |
| item.cerifentitytype | Publications | - |
| item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
| item.fulltext | No Fulltext | - |
| item.languageiso639-1 | en | - |
| Aparece en las colecciones: | (CENQUIOR) Artículos (IQM) Artículos | |
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