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Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/33631
Title: The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity
Authors: Alonso De Diego, Sergio A.; Gutiérrez-Rodríguez, Marta; Pérez de Vega, M. Jesús; González-Muñiz, Rosario; Herranz, Rosario; Martín-Martínez, Mercedes; Cenarruzabeitia, Edurne; Frechilla, Diana; Río, Joaquín del; Jimeno, M. Luisa; García-López, M. Teresa
Keywords: Neuroprotection
Glutamate receptors binding
Issue Date: 1-Jul-2006
Publisher: Elsevier
Citation: Bioorganic & Medicinal Chemistry Letters 16(13): 3396-3400 (2006)
Abstract: The influence of several modifications on the GPE tripeptide structure upon the binding to GluRs and on their neuroprotective effects has been studied. The results indicated that the prevention of neuronal death showed by GPE and some analogues is not directly related to their affinity at glutamate receptors.
Publisher version (URL): http://dx.doi.org/10.1016/j.bmcl.2006.04.033
URI: http://hdl.handle.net/10261/33631
DOI: 10.1016/j.bmcl.2006.04.033
ISSN: 0960-894X
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