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Title

Insulin-like growth factor-I gene delivery to astrocytes reduces their inflammatory response to lipopolysaccharide

AuthorsBellini, María José CSIC ORCID; Herenu, Claudia B.; Goya, Rodolfo G.; García-Segura, Luis M. CSIC ORCID
KeywordsInsulin-like
IGF-I
Issue Date3-Mar-2011
PublisherBioMed Central
CitationJournal of Neuroinflammation 8(21): (2011)
AbstractInsulin-like growth factor-I (IGF-I) exerts neuroprotective actions in the central nervous system that are mediated at least in part by control of activation of astrocytes. In this study we have assessed the efficacy of exogenous IGF-I and IGF-I gene therapy in reducing the inflammatory response of astrocytes from cerebral cortex.
Publisher version (URL)http://dx.doi.org/10.1186/1742-2094-8-21
URIhttp://hdl.handle.net/10261/33112
DOI10.1186/1742-2094-8-21
E-ISSN1742-2094
Appears in Collections:(IC) Artículos




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