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Title

A polymeric chip for micromanipulation and particle sorting by ultrasounds based on a multilayer configuration

AuthorsGonzález Gómez, Icíar; Fernández Ledesma, Luis José; Gómez, Tomás Enrique; Berganzo Ruiz, Javier; Soto Martínez, José Luis; Carrato, Alfredo
KeywordsUltrasonic-lab-on-chip
Actuators
Mass transfer
Microfluidics
Sorting
Separation
Issue Date29-Jan-2010
PublisherElsevier
CitationSensors and Actuators B: Chemica 144(1) : 310-317 (2010)
AbstractA new polymer microchip is presented in this paper for separation and particle sorting in flowing suspensions. It includes a microchannel where a fluid-sample containing particles flows in parallel with another liquid. The working principle is based on an ultrasonic actuation on the cross-section of the chip, which behaves as a multilayer system. That part of the wave established within the channel includes a node of pressure strategically located within the collector fluid path, where the target particles collected to be extracted from their host sample. The use of a polymer as the constitutive material of the chip, new in this type of devices, allows a channel width somewhat larger than a quarter of a wavelength, which does not fit any of the conventional models but it represents an intermediate situation. The device has been fabricated by standard SU-8 photolithography using PMMA as substrate. In the experiments, polystyrene particles of 20 μm in diameter have been extracted from aqueous suspensions containing 6-μm sized particles by a strategic application of ultrasonic waves. A high efficiency of particle separation, over 95%, at different concentrations and flow rates, prove the feasibility of the device to carry out sorting processes on flowing suspensions.
Publisher version (URL)http://dx.doi.org/10.1016/j.snb.2009.10.042
URIhttp://hdl.handle.net/10261/32181
DOI10.1016/j.snb.2009.10.042
ISSN0925-4005
Appears in Collections:(IA) Artículos
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