´Derivatives of4-4'-BIPYRIDYL-2-2'-BISOXAZOLES AND 4-4'-BIPYRIDYL-2-2'-BISTIAZOLES as antineoplastic agents.

Abstract

[ES]The invention relates to novel derivatives of 4-4'-bipyridyl-2-2'-bisoxazoles and 4-4'-bipyridyl-2-2'-bistiazoles, having general formula I with antiproliferative activity and, more specifically, malignant cells such as HT-29. The invention also relates to the industrial production method for same and to the use thereof in the development of pharmaceutical compounds for the treatment of human tumours.[EN]La presente invención presenta nuevos derivados de 4-4'-bipiridil-2-2'-bisoxazoles y 4-4'-bipiridil-2-2'-bistiazoles de fórmula general I con actividad antiproliferativa, y concretamente, de células malignas como HT-29. Por otro lado, se indica en la presente patente el mecanismo de su producción industrial y su uso para el desarrollo de compuestos farmacéuticos para el tratamiento de tumores humanos.