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Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/31337
Title: Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices
Authors: Sepúlveda Martínez, Borja; Sánchez del Río, José; Moreno, M.; Blanco, Francisco; Mayora, K.; Domínguez, Carlos; Lechuga, Laura M.
Keywords: Optical biosensors
Integrated Mach–Zehnder interferometer
SU-8 microfluidics
Issue Date: 2006
Publisher: Institute of Physics Publishing
Citation: Journal of Optics - A - Pure and Applied Optics 8(7): S561–S566 (2006)
Abstract: We present highly sensitive optical biosensors able to be fully integrated in lab-on-a-chip microsystems using standard CMOS compatible processes. These optical biosensors are based on integrated Mach–Zehnder interferometers, which have been designed to have high surface sensitivity and monomode behaviour. As a biosensing application of the devices we show the real-time detection of the covalent immobilization and hybridization of DNA strands without labelling. In order to achieve a lab-on-a-chip portable microsystem, we present the integration of the sensor with a CMOS compatible microfluidic system using SU-8 photolithography patterned layers.
Description: 6 páginas, 8 figuras.
Publisher version (URL): http://dx.doi.org/10.1088/1464-4258/8/7/S41
URI: http://hdl.handle.net/10261/31337
ISSN: 1464-4258
DOI: 10.1088/1464-4258/8/7/S41
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