Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/29536
Title: Highly reactive 4-membered ring nitrogen-containing heterocycles: Synthesis and properties
Authors: Alcaide, Benito, Almendros, Pedro, Arangocillo, Cristina
Keywords: Azetidines
Heterocycles
β-lactams
Rearrangements
Stereoselectivity
Strain
Issue Date: 2010
Publisher: BioMed Central
Abstract: 4-Membered nitrogen-containing heterocycles, such as β-lactams (ie, 2-azetidinones) and azetidines, are useful substrates in organic chemistry for the design and preparation of biologically active compounds by functionalization of the different positions of the ring. In addition, these compounds are versatile building blocks for the synthesis of other types of nitrogen-containing compounds with potential biological properties. This review summarizes recent data regarding the preparation and properties of 4-membered nitrogen-containing heterocyclic rings, as well as their biological activities.
Description: 13 páginas, 15 esquemas.-- El documento en word es el artículo post-print.
Publisher version (URL): http://www.biomedcentral.com/curropindrugdiscovdevel/
URI: http://hdl.handle.net/10261/29536
ISSN: 1367-6733
Citation: Current Opinion in Drug Discovery and Development 13(6): 685-697 (2010)
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