English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/27353
Share/Impact:
Statistics
logo share SHARE   Add this article to your Mendeley library MendeleyBASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Direct inhibition of (Z)-9 desaturation of (E)-11-tetradecenoic acid by methylenehexadecenoic acids in the biosynthesis of Spodoptera littoralis sex pheromone

AuthorsFabriàs, Gemma ; Gosalbo, Laura; Quintana, Jordi; Camps Díez, Francisco
KeywordsInhibition
Desaturase
Sex pheromone
Cyclopropene fatty acid
Biosynthesis
Spodoptera littoralis
Lepidoptera
Insect
Issue DateJul-1996
PublisherAmerican Society for Biochemistry and Molecular Biology
CitationJournal of Lipid Research 37(7): 1503-1509 (1996)
AbstractAnalysis by gas chromatography coupled to mass spectrometry demonstrated that 11,12-methylenehexadec-11-enoic acid and 12,13-methylenehexadec-12-enoic acid are beta-oxidized in Spodoptera littoralis sex pheromone gland to 9, 10-methylenetetradec-10-enoic acid and 10,11-methylenetetradec-10-enoic acid, respectively. This result supported our previous hypothesis that inhibition of the (Z)-9 desaturation of (E)-11-tetradecenoic acid by those C-16 fatty acids is actually caused by their corresponding beta-oxidation products. However, although (2,2,3,3-2H4)-11,12-methylenehexadec-11-enoic acid was not chain-shortened to the C-14 derivative, its activity as inhibitor of the (Z)-9 desaturation reaction was similar to that exhibited by 11,12-methylenehexadec-11-enoic acid. Therefore, the C-16 cyclopropene fatty acids may inhibit the (Z)-9 desaturation enzyme by themselves, probably through interaction of the cyclopropene ring with a binding site of the enzyme with the substrate double bond.
Description7 pages, 7 figures. PMID: 8827522 [PubMed].
Publisher version (URL)http://www.jlr.org/cgi/reprint/37/7/1503
URIhttp://hdl.handle.net/10261/27353
ISSN0022-2275 (Print)
Appears in Collections:(IQAC) Artículos
Files in This Item:
There are no files associated with this item.
Show full item record
Review this work
 


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.