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Please use this identifier to cite or link to this item:
http://hdl.handle.net/10261/2712
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| Title: | DNA molecule with insulating activity against chromosomal position effects in gene transfer processes in animal cells
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| Other Titles: | Molécula de ADN con actividad aisladora de efectos de posición cromosomales en procesos de transferencia génica en células animales |
| Authors: | Montoliu, Lluís
Giraldo, Patricia
Busturia, Ana |
| Keywords: | Animal cells
Gene transfer processes
Chromosomal position effects
Insulating activity
Transgene expression |
| Issue Date: | 28-Nov-2002 |
| Citation: | International Publication Number: WO 2002/095031 A1 |
| Abstract: | [EN] The invention relates to a DNA molecule or a fragment of said DNA molecule obtained from the LCR (Locus Control Region) sequence of the mouse tyrosinase gene. Said sequence has insulating activity against chromosomal position effects in gene transfer processes in animal cells. The DNA molecule can be used to introduce transgenes and to reduce the variability of the transgene expression in animal cells.
[ES] Molécula de ADN o un fragmento de la misma obtenida a partir de la secuencia LCR (Locus Control Region) del gen de la tirosinasa de ratón. Dicha secuencia tiene actividad aisladora de efectos de posición cromosomales en procesos de transferencia génica en células de animales. La molécula de ADN puede utilizarse para introducir transgenes y reducir la variabilidad de la expresión de transgenes en células de animales. |
| Description: | Filing Date: 2002-05-10.-- Priority Data
ES P200101133 (2001-05-18). |
| URI: | http://hdl.handle.net/10261/2712 |
| Appears in Collections: | (CNB) Patentes
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