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Título : Synthetic approaches to heterocyclic ligands for Gd-based MRI contrast agents
Autor : Pérez-Mayoral, Elena, Soler-Padrós, Jordi, Negri, Viviana, Cerdán, Sebastián, Ballesteros, Paloma
Palabras clave : Lanthanide complexes
Contrast agents
Heterocyclic ligands
MR imaging
Fecha de publicación : 9-Aug-2007
Editor: Multidisciplinary Digital Publishing Institute
Citación : Molecules 12(8): 1771-1795 (2007)
Resumen: Magnetic Resonance Imaging (MRI) methods are currently used in the clinic for the non invasive detection and characterization of a wide variety of pathologies. Increases in the diagnostic efficiency of MRI have been helped by both the design of dedicated MR sequences revealing specific aspects of the pathology and by the development of more sensitive and selective Contrast Agents (CAs), capable of more precisely delineating the borderline regions. In the present review we focus on the synthetic strategies used to obtain MRI CAs containing heterocyclic rings.
Descripción : 25 pages, 7 figures, 25 schemes.
Versión del editor:
ISSN: 1420-3049
DOI: 10.3390/12081771
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