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8-Amino guanine accelerates tetramolecular G-quadruplex formation

AuthorsGros, Julien; Aviñó, Anna; López de la Osa, Jaime ; González, Carlos ; Lacroix, Laurent; Pérez, Alberto; Orozco, Modesto; Eritja Casadellà, Ramón; Mergny, Jean-Louis
KeywordsG-quadruplex formation
DNA structure
Isothermal difference spectra
Issue Date15-Apr-2008
PublisherRoyal Society of Chemistry (UK)
CitationChemical Communications 25: 2926-2928 (2008)
AbstractWe demonstrate here that 8-amino guanine (R) strongly accelerates quadruplex formation, which makes this nucleobase the most attractive replacement for guanine in the context of tetramolecular parallel quadruplexes.
Description2 pages, 4 figures, 1 table.-- PMID: 18566727 [PubMed].
Publisher version (URL)http://dx.doi.org/10.1039/b801221k
Appears in Collections:(IQAC) Artículos
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