Biología y Biomedicina >
Centro de Investigaciones Biológicas (CIB) >
(CIB) Artículos >
Open Access item The “Gene” Experiment in the Spanish Soyuz Mission to the International Space Station. Effects of cold transportation
Laván, David A.
Medina, F. Javier
Van Loon, Jack JWA
Leandro, L. J.
|Citation:||Microgravity Science and Technology|
|Abstract:||If exploration of outer space is going to be a major human
enterprise in the future, it is important to establish the nature
of the biological response to the space environment. In one of
the recent Soyuz missions to serve the ISS, the Spanish Soyuz
Mission in October 2003, we sent a group of Drosophila pupae
that underwent almost complete development there.
Microarray analyses of the RNAs extracted from flies fixed in
the ISS revealed that a relatively large set of genes (15% of
the total number assayed) suffered a significant expression
change in these conditions. Furthermore, the samples had to be
transported to the launch site and it was necessary to slow
down their development by exposing them to a lower
temperature, fully compatible with pupal development. Such a
pre-exposure had an effect by itself on the pattern of gene
expression observed after pupal development at normal
temperature, but the two environmental factors seemed to act
synergistically. These findings indicate the importance of
maintaining a vigorous scientific program in the ISS to
understand the consequences of the modified environment in
outer space on living organisms.|
|Description:||Manuscript version. Final Article available on the publisher site.
|Publisher version (URL):||10.1007/BF02919481|
|Appears in Collections:||(CIB) Artículos|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.