Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/21986
Share/Export:
logo share SHARE BASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Title

Gene Expression Variations During Drosophila Metamorphosis in Space. The GENE Experiment in the Spanish Cervantes Mission to the ISS

AuthorsHerranz, Raúl CSIC ORCID ; Benguria, Alberto; Fernandez-Pineda, Emilio; Medina, F. Javier CSIC ORCID CVN ; Gasset, Gilbert; van Loon, Jack JWA; Zaballos, Ángel; Marco, Roberto CSIC
KeywordsDrosophila
microgravity
Issue Date2005
CitationJ Gravit Physiol
Series12
1
AbstractThe ISS expedition 8, a 10 days “taxi” flight Soyuz Mission to the International Space Station (ISS) to replace the two-member ISS crew, took place during October 2003. Within the Spanish Cervantes Scientific Mission, in this crew exchanging flight, some biological experiments were performed. The third member of the expedition, the Spanish born ESA astronaut Pedro Duque, returned with the Soyuz 7 capsule and the experiment containing transport box after 11 days on microgravity. In the GENE experiment, we intended to determine how microgravity affects the organism rebuilding processes that occurs during Drosophila metamorphosis. In addition to the ISS samples, some control experiments were performed including a 1g Ground control parallel to the ISS flight samples, a Random Position Machine microgravity si m u l a t e d c o n t r o l a n d a p a r a l l e l Hypergravity (10g) exposed samples experiment. We have used extracted RNA from these samples to test the differences among gene expression during Drosophila development with one of the current more powerful technology, a Drosophila complete genome microarray (version 1.0, AffymetrixTM). A preliminary analysis of the results indicates that around five hundred genes change their expression profiles being especially affected the mitochondrial ribosomal ones.
DescriptionManuscript long version, prior to reduction due to the mandatory final 2-pages published version
URIhttp://hdl.handle.net/10261/21986
ISSN1077-9248
Appears in Collections:(CIB) Artículos




Files in This Item:
File Description SizeFormat
Ref9-Herranz2005_edited.pdf179,57 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work

Page view(s)

344
checked on May 28, 2022

Download(s)

119
checked on May 28, 2022

Google ScholarTM

Check


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.