Expanding the Spectrum of Light-Driven Peroxygenase Reactions

Abstract

[EN] Peroxygenases require a controlled supply of HO to operate efficiently. Here, we propose a photocatalytic system for the reductive activation of ambient O to produce HO which uses the energy provided by visible light more efficiently based on the combination of wavelength-complementary photosensitizers. This approach was coupled to an enzymatic system to make formate available as a sacrificial electron donor. The scope and current limitations of this approach are reported and discussed.