English   español  
Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/212129
Share/Impact:
Statistics
logo share SHARE logo core CORE   Add this article to your Mendeley library MendeleyBASE

Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL
Exportar a otros formatos:

Title

Cloning and structural analysis of the gene encoding the ribosomal protein S6 from the parasite Leishmania Infantum

AuthorsGonzález-Aseguinolaza; Taladriz, Soraya; Marquet, Alberto; Larraga, Vicente
KeywordsMessenger-RNA
Phosphorylation
Stimulation
Sequence
Identification
Promastigotes
Translation
Elongation
Alignment
Donovani
Issue Date30-Jul-1998
PublisherElsevier
CitationBiochem Biophys Res Commun 248 (3) 464-8 (1998)
AbstractWe have cloned the S6 ribosomal protein encoding gene from a Leishmania infantum cDNA library. This parasite protozoon, responsible for leishmaniasis in Europe, is able to undergo developmental changes in vitro and results a good model to study cell differentiation processes. The LiS6 protein sequence indicates its pertinence to the S6 protein family, related to the early mechanisms of cell division, differentiation and activation, and shows an intermediate position between the yeasts and higher eukaryotes. Thus, LiS6 protein has the same amino acid length as that of the higher eukaryotes and certain common features such nucleus entrance sequences and several kinase phosphorylation sites. However, the key functional protein kinase C phosphorylation sites are at different locations and present several threonine instead of the usual serine residues. The gene structural analysis suggest the presence of three different encoding genes that do not present remarkable changes along the different phases of the parasite.
Description5 p.-4 fig.
Publisher version (URL)https://doi.org/10.1006/bbrc.1998.8927
URIhttp://hdl.handle.net/10261/212129
DOI10.1006/bbrc.1998.8927
ISSN0006-291X
E-ISSN1090-2104
Appears in Collections:(CIB) Artículos
Files in This Item:
File Description SizeFormat 
accesoRestringido.pdfRestringido15,38 kBAdobe PDFThumbnail
View/Open
Show full item record
Review this work
 

Related articles:


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.