Interference of MERS-CoV accessory genes with the innate immune response and their contribution to virulence

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Título:	Interference of MERS-CoV accessory genes with the innate immune response and their contribution to virulence
Autor:	Solá Gurpegui, Isabel CSIC ORCID ; Cantón, Javier ; Gutierrez-Alvarez, Francisco J. ; Morales, Lucía CSIC ORCID ; Zúñiga Lucas, Sonia CSIC ORCID ; Sánchez-Aparicio, María T.; García-Sastre, Adolfo; Enjuanes Sánchez, Luis CSIC ORCID
Fecha de publicación:	19-oct-2016
Citación:	6th European Congress of Virology (2016)
Resumen:	Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging coronavirus infecting humans, associated with acute pneumonia, occasionally renal failure, and a high mortality rate around 36% (as of May 16th 2016, 1733 laboratory-confirmed cases have been reported, including at least 628 related deaths), which is considered a public health threat. A reverse genetics system for MERS- CoV has been developed by the construction of an infectious cDNA clone inserted into a bacterial artificial chromosome, providing a tool to study the virus molecular biology and to develop attenuated viruses as vaccine candidates.
Descripción:	Trabajo presentado en el 6th European Congress of Virology, celebrado en Hamburgo (Alemania), del 19 al 22 de octubre de 2016
URI:	http://hdl.handle.net/10261/204629
Aparece en las colecciones:	(CNB) Comunicaciones congresos (PTI Salud Global) Colección Especial COVID-19