Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/20296
Share/Export:
logo share SHARE logo core CORE BASE
Visualizar otros formatos: MARC | Dublin Core | RDF | ORE | MODS | METS | DIDL | DATACITE
Title

Triphenyltin and tributyltin, single and in combination, promote imposex in the gastropod Bolinus brandaris

AuthorsMachado Santos, Miguel; Reis-Henriques, Maria Armanda; Vieira, Maria Natividade; Solé, Montserrat CSIC ORCID
KeywordsImposex
Triphenyltin
Tributyltin
Chemical mixtures
Bioindicators
Bolinus brandaris
APGWamide
Acetylcholinesterase
Issue DateJun-2006
PublisherElsevier
CitationEcotoxicology and Environmental Safety 64(2): 155–162 (2006)
AbstractSpecimens of Bolinus brandaris (neogastropod) were injected with a single dose of 500 ng/g body weight (b.w.) of tributyltin chloride (TBTCl) or triphenyltin chloride (TPTCl), or a mixture of both compounds (250 ng TBT/g b.w.+250 ng TPT/g b.w.), for a period of up to 31 days. At the end of 4 weeks, significant increases in the female penis size of those gastropods injected with TBT (Po0:05), TPT (Po0:05), or the mixture TBT+TPT (Po0:01) were recorded. In parallel, a group of animals was injected with the neuropeptide APGWamide but this compound failed to promote imposex, suggesting that APGWamide is not involved in imposex promotion in B. brandaris. Acetylcholinesterase activity, a biomarker of neurotoxicity, was determined in the neuroganglia at the end of the experiment, but no significant differences among treatments were found. Overall, these results support the hypothesis that TPT also acts as an endocrine disrupter in this neogastropod species. Our observations also highlight, for the first time, synergistic effects of organotin mixtures having imposex promotion as an endpoint.
Description8 pages, 2 tables
Publisher version (URL)https://doi.org/10.1016/j.ecoenv.2005.02.003
URIhttp://hdl.handle.net/10261/20296
DOI10.1016/j.ecoenv.2005.02.003
ISSN0147-6513
Appears in Collections:(ICM) Artículos
(ICMAN) Artículos

Show full item record
Review this work

SCOPUSTM   
Citations

45
checked on Jun 28, 2022

WEB OF SCIENCETM
Citations

40
checked on Jul 3, 2022

Page view(s)

306
checked on Jul 4, 2022

Google ScholarTM

Check

Altmetric

Dimensions


WARNING: Items in Digital.CSIC are protected by copyright, with all rights reserved, unless otherwise indicated.