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dc.contributor.authorAbascal, Estefaníaes_ES
dc.contributor.authorHerranz, Martaes_ES
dc.contributor.authorAcosta, Fermínes_ES
dc.contributor.authorAgapito, Juanes_ES
dc.contributor.authorCabibbe, Andrea M.es_ES
dc.contributor.authorMonteserin, Johanaes_ES
dc.contributor.authorRuiz Serrano, María Jesúses_ES
dc.contributor.authorGijón, Palomaes_ES
dc.contributor.authorFernández-González, Franciscoes_ES
dc.contributor.authorLozano, Nuriaes_ES
dc.contributor.authorChiner-Oms, Álvaroes_ES
dc.contributor.authorCáceres, Tatianaes_ES
dc.contributor.authorGómez Pintado, Pilares_ES
dc.contributor.authorAcín, Enriquees_ES
dc.contributor.authorValencia, Eddyes_ES
dc.contributor.authorMuñoz, Patriciaes_ES
dc.contributor.authorComas, Iñakies_ES
dc.contributor.authorCirillo, Daniela M.es_ES
dc.contributor.authorRitacco, Vivianaes_ES
dc.contributor.authorGotuzzo, Eduardoes_ES
dc.contributor.authorGarcía de Viedma, Daríoes_ES
dc.date.accessioned2020-02-21T08:48:19Z-
dc.date.available2020-02-21T08:48:19Z-
dc.date.issued2020-02-17-
dc.identifier.citationScientific Reports 10(1):2704 (2020)es_ES
dc.identifier.urihttp://hdl.handle.net/10261/201469-
dc.description8 páginas, 4 figuras, 1 tabla. Información suplementaria accesible en: https://doi.org/10.1038/s41598-020-59373-wes_ES
dc.description.abstractIt is relevant to evaluate MDR-tuberculosis in prisons and its impact on the global epidemiology of this disease. However, systematic molecular epidemiology programs in prisons are lacking. A health-screening program performed on arrival for inmates transferred from Peruvian prisons to Spain led to the diagnosis of five MDR-TB cases from one of the biggest prisons in Latin America. They grouped into two MIRU-VNTR-clusters (Callao-1 and Callao-2), suggesting a reservoir of two prevalent MDR strains. A high-rate of overexposure was deduced because one of the five cases was coinfected by a pansusceptible strain. Callao-1 strain was also identified in 2018 in a community case in Spain who had been in the same Peruvian prison in 2002-5. A strain-specific-PCR tailored from WGS data was implemented in Peru, allowing the confirmation that these strains were currently responsible for the majority of the MDR cases in that prison, including a new mixed infection.es_ES
dc.description.sponsorshipThis work was supported by ERANet-LAC [ELAC2015/T08–0664, E035-ERANet-LAC/J110-2016/FONDECYT, PER-2012-ELAC2015/T08-0664] and Instituto de Salud Carlos III [AC16/00057, FIS15/01554, FIS13/01207] and cofunded by European Regional Development Funds from the European Commission: “A way of making Europe”. FA holds a grant from IFARHUSENACYT [270-2016-293].es_ES
dc.language.isoenges_ES
dc.publisherNature Publishing Groupes_ES
dc.relationinfo:eu-repo/grantAgreement/EC/FP7/609484es_ES
dc.relation.isversionofPublisher's versiones_ES
dc.rightsopenAccesses_ES
dc.titleScreening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infectionses_ES
dc.typeartículoes_ES
dc.identifier.doi10.1038/s41598-020-59373-w-
dc.description.peerreviewedPeer reviewedes_ES
dc.relation.publisherversionhttp://dx.doi.org/10.1038/s41598-020-59373-wes_ES
dc.identifier.e-issn2045-2322-
dc.rights.licensehttp://creativecommons.org/licenses/by/4.0/es_ES
dc.contributor.funderInstituto de Salud Carlos IIIes_ES
dc.contributor.funderEuropean Commissiones_ES
dc.contributor.funderSecretaría Nacional de Ciencia y Tecnología (Panamá)es_ES
dc.relation.csices_ES
oprm.item.hasRevisionno ko 0 false*
dc.identifier.funderhttp://dx.doi.org/10.13039/501100004587es_ES
dc.identifier.funderhttp://dx.doi.org/10.13039/501100000780es_ES
dc.contributor.orcidComas, Iñaki [0000-0001-5504-9408]es_ES
dc.contributor.orcidChiner-Oms, Álvaro [0000-0002-0463-0101]es_ES
dc.identifier.pmid32066749-
dc.type.coarhttp://purl.org/coar/resource_type/c_6501es_ES
item.openairetypeartículo-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextWith Fulltext-
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