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http://hdl.handle.net/10261/201469
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dc.contributor.author | Abascal, Estefanía | es_ES |
dc.contributor.author | Herranz, Marta | es_ES |
dc.contributor.author | Acosta, Fermín | es_ES |
dc.contributor.author | Agapito, Juan | es_ES |
dc.contributor.author | Cabibbe, Andrea M. | es_ES |
dc.contributor.author | Monteserin, Johana | es_ES |
dc.contributor.author | Ruiz Serrano, María Jesús | es_ES |
dc.contributor.author | Gijón, Paloma | es_ES |
dc.contributor.author | Fernández-González, Francisco | es_ES |
dc.contributor.author | Lozano, Nuria | es_ES |
dc.contributor.author | Chiner-Oms, Álvaro | es_ES |
dc.contributor.author | Cáceres, Tatiana | es_ES |
dc.contributor.author | Gómez Pintado, Pilar | es_ES |
dc.contributor.author | Acín, Enrique | es_ES |
dc.contributor.author | Valencia, Eddy | es_ES |
dc.contributor.author | Muñoz, Patricia | es_ES |
dc.contributor.author | Comas, Iñaki | es_ES |
dc.contributor.author | Cirillo, Daniela M. | es_ES |
dc.contributor.author | Ritacco, Viviana | es_ES |
dc.contributor.author | Gotuzzo, Eduardo | es_ES |
dc.contributor.author | García de Viedma, Darío | es_ES |
dc.date.accessioned | 2020-02-21T08:48:19Z | - |
dc.date.available | 2020-02-21T08:48:19Z | - |
dc.date.issued | 2020-02-17 | - |
dc.identifier.citation | Scientific Reports 10(1):2704 (2020) | es_ES |
dc.identifier.uri | http://hdl.handle.net/10261/201469 | - |
dc.description | 8 páginas, 4 figuras, 1 tabla. Información suplementaria accesible en: https://doi.org/10.1038/s41598-020-59373-w | es_ES |
dc.description.abstract | It is relevant to evaluate MDR-tuberculosis in prisons and its impact on the global epidemiology of this disease. However, systematic molecular epidemiology programs in prisons are lacking. A health-screening program performed on arrival for inmates transferred from Peruvian prisons to Spain led to the diagnosis of five MDR-TB cases from one of the biggest prisons in Latin America. They grouped into two MIRU-VNTR-clusters (Callao-1 and Callao-2), suggesting a reservoir of two prevalent MDR strains. A high-rate of overexposure was deduced because one of the five cases was coinfected by a pansusceptible strain. Callao-1 strain was also identified in 2018 in a community case in Spain who had been in the same Peruvian prison in 2002-5. A strain-specific-PCR tailored from WGS data was implemented in Peru, allowing the confirmation that these strains were currently responsible for the majority of the MDR cases in that prison, including a new mixed infection. | es_ES |
dc.description.sponsorship | This work was supported by ERANet-LAC [ELAC2015/T08–0664, E035-ERANet-LAC/J110-2016/FONDECYT, PER-2012-ELAC2015/T08-0664] and Instituto de Salud Carlos III [AC16/00057, FIS15/01554, FIS13/01207] and cofunded by European Regional Development Funds from the European Commission: “A way of making Europe”. FA holds a grant from IFARHUSENACYT [270-2016-293]. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Nature Publishing Group | es_ES |
dc.relation | info:eu-repo/grantAgreement/EC/FP7/609484 | es_ES |
dc.relation.isversionof | Publisher's version | es_ES |
dc.rights | openAccess | es_ES |
dc.title | Screening of inmates transferred to Spain reveals a Peruvian prison as a reservoir of persistent Mycobacterium tuberculosis MDR strains and mixed infections | es_ES |
dc.type | artículo | es_ES |
dc.identifier.doi | 10.1038/s41598-020-59373-w | - |
dc.description.peerreviewed | Peer reviewed | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1038/s41598-020-59373-w | es_ES |
dc.identifier.e-issn | 2045-2322 | - |
dc.rights.license | http://creativecommons.org/licenses/by/4.0/ | es_ES |
dc.contributor.funder | Instituto de Salud Carlos III | es_ES |
dc.contributor.funder | European Commission | es_ES |
dc.contributor.funder | Secretaría Nacional de Ciencia y Tecnología (Panamá) | es_ES |
dc.relation.csic | Sí | es_ES |
oprm.item.hasRevision | no ko 0 false | * |
dc.identifier.funder | http://dx.doi.org/10.13039/501100004587 | es_ES |
dc.identifier.funder | http://dx.doi.org/10.13039/501100000780 | es_ES |
dc.contributor.orcid | Comas, Iñaki [0000-0001-5504-9408] | es_ES |
dc.contributor.orcid | Chiner-Oms, Álvaro [0000-0002-0463-0101] | es_ES |
dc.identifier.pmid | 32066749 | - |
dc.type.coar | http://purl.org/coar/resource_type/c_6501 | es_ES |
item.openairetype | artículo | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
item.grantfulltext | open | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | With Fulltext | - |
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2020 Sci Rep 10-2704.pdf | 1,42 MB | Adobe PDF | Visualizar/Abrir |
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