Please use this identifier to cite or link to this item: http://hdl.handle.net/10261/19871
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Título : Gut Microbiota and Probiotics in Modulation of Epithelium and Gut-Associated Lymphoid Tissue Function
Autor : Sanz, Yolanda, Palma, Giada de
Palabras clave : Gut microbiota
Probiotics
Mucosal immunity
Regulatory T cells
Fecha de publicación : Dec-2009
Editor: Taylor & Francis
Citación : International Reviews of Immunology 28 (6): 397-413 (2009)
Resumen: The intestinal tract mucosa is exposed to a vast number of environmental antigens and a large community of commensal bacteria. The mucosal immune system has to provide both protection against pathogens and tolerance to harmless bacteria. Immune homeostasis depends on the interaction of indigenous commensal and transient bacteria (probiotics) with various components of the epithelium and the gut-associated lymphoid tissue. Herein, an update is given of the mechanisms by which the gut microbiota and probiotics are translocated through the epithelium, sensed via pattern-recognition receptors, and activate innate and adaptive immune responses.
Descripción : 17 pages, 2 figures.
Versión del editor: http://dx.doi.org/10.3109/08830180903215613
URI : http://hdl.handle.net/10261/19871
ISSN: 0883-0185
DOI: 10.3109/08830180903215613
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